The short answer
- Radiesse is calcium hydroxylapatite, not hyaluronic acid. Mineral microspheres in a gel, made by Merz. The gel lifts on the day; the microspheres then prompt new collagen over the following months.
- It is built for structure: cheekbones, the jawline, the nasolabial and marionette folds and the backs of the hands, plus diluted versions for crepey skin on the neck and décolletage. It is not for the lips, the under-eyes or the nose.
- Current Dubai prices run from AED 1,499 to 4,500 per syringe (published by clinics, September 2026), most between AED 2,500 and 3,600. A syringe holds 1.5 ml, not the 1 ml of most hyaluronic acid syringes.
- Expect about 12 to 18 months, the range Merz gives.
- It cannot be dissolved, so the injector matters even more than with hyaluronic acid filler. Check the clinic and the injector's DHA licence before you book.
Radiesse sits in an unusual place on a Dubai clinic menu. It is injected like a filler and lifts on the day, but it is not hyaluronic acid, it keeps working for months by prompting new collagen, and it cannot be dissolved if something goes wrong. That last point matters more than any other.
This guide covers what it is made of, where it works and where it should never go, published Dubai prices, how it compares with Sculptra and hyaluronic acid filler, and what to check before you book. The regulatory facts come from the US Food and Drug Administration (FDA) and Merz's UAE product leaflet; the prices are the ones clinics publish, not a quote from any single clinic.
What Radiesse is made of, and who makes it
Radiesse is a firm injectable implant made of calcium hydroxylapatite (CaHA) microspheres, 25 to 45 microns across, suspended in a gel of sterile water, glycerin and sodium carboxymethylcellulose, and it is made by Merz Aesthetics. Calcium hydroxylapatite is a mineral the body already contains, mainly in bone; the version in Radiesse is synthetic.
Radiesse (+) is the same product pre-mixed with the local anaesthetic lidocaine. Both are manufactured by Merz North America in the United States, and Merz's Middle East company publishes a UAE edition of the instructions for use. That leaflet lists 0.8 ml, 1.5 ml and 3.0 ml syringes; 1.5 ml is the size Dubai clinics quote when they name one. These are the US approvals, from the FDA's records:
| FDA approval date | What was approved |
|---|---|
| 22 December 2006 | Moderate to severe facial wrinkles and folds, such as the nasolabial folds |
| 22 December 2006 | Restoring facial volume lost to HIV-associated lipoatrophy (a separate approval) |
| 30 January 2015 | Radiesse (+), the lidocaine version, for facial wrinkles and folds |
| 4 June 2015 | Restoring volume in the backs of the hands |
| 1 September 2021 | Radiesse (+) for moderate to severe loss of jawline contour, adults over 21 |
| 31 March 2026 | Radiesse diluted 1:2 with saline for wrinkles on the décolletage, age 22 and over |
The UAE leaflet lists the nasolabial folds, cheek augmentation, marionette lines, the jawline, the backs of the hands and HIV-related facial fat loss. Product registration in the UAE is handled federally and there is no simple public lookup for a single syringe, so your protection is the sealed product and a licensed doctor, as our guide to approved Botox and filler brands in the UAE explains.
How Radiesse works: lift now, collagen later
Radiesse works in two phases: the gel gives an immediate lift, and the microspheres then act as a scaffold that your own collagen grows around. Merz's UAE leaflet describes the gel being dissipated and replaced with new soft tissue while the calcium hydroxylapatite stays in place. The body later breaks the microspheres down too, so the result is long-lasting but not permanent; a 2024 review notes that imaging has shown the material fully resorbed within about two and a half years.
Two consequences follow. Injectors are told not to overfill, because the area keeps improving for several weeks, so what you see at the end of the appointment should be close to the final shape. And the FDA describes Radiesse as a semi-solid, cohesive implant: an asset deep over bone along a cheekbone or jawline, a liability in soft, mobile tissue such as the lips.
Where Radiesse is used, and where it should not go
Radiesse is used where the face needs structure, mostly deep over bone, plus diluted versions for crepey skin on the neck, décolletage and arms. It is not a lip filler and not an under-eye filler.
| Area | Status | What to know |
|---|---|---|
| Cheekbones and mid-face | In Merz's UAE leaflet | Placed deep for lift. Compare options in our cheek fillers guide. |
| Jawline and chin | FDA-approved for jawline contour (Radiesse (+), 2021) | Holds a defined edge. See jawline filler in Dubai. |
| Nasolabial folds, marionette lines | FDA-approved for folds (2006); in the UAE leaflet | The original use, with small volumes. |
| Temples | Not a listed indication | Some injectors use it; ask why not hyaluronic acid. |
| Backs of the hands | FDA-approved (2015); in the UAE leaflet | More swelling and downtime than the face. |
| Neck, décolletage, arms (diluted) | Décolletage FDA-approved at 1:2 (2026); the rest not approved | Skin quality, very little volume. |
| Lips | Not recommended | Merz: not known if safe or effective here. |
| Under-eyes, tear troughs | Not recommended | Merz: not known if safe or effective around the eyes. |
| Nose, between the brows | Excluded in the UAE leaflet | A higher rate of skin necrosis has been reported. |
Both the lips and the tear troughs are occasionally offered, so a plain warning: an expert consensus on Radiesse notes that 45% of reported nodules occurred in dynamic, frequently moving parts of the face. A lump of hyaluronic acid in a lip can usually be dissolved; a lump of Radiesse cannot. A clinic that suggests it for either area is a reason to see someone else.
What Radiesse costs in Dubai in 2026
The Radiesse filler price in Dubai currently runs from AED 1,499 to AED 4,500 per syringe on the price lists clinics published in September 2026, with most clinics between about AED 2,500 and AED 3,600. The lowest figures are promotional "from" prices. At the top, one clinic lists AED 6,000 per 1.5 ml syringe as its full price while advertising it at AED 3,600. Some clinics price diluted treatments per session instead: one Dubai list shows AED 1,500 to 2,500 for the neck and AED 2,000 to 3,000 for the décolletage.
A Radiesse syringe usually holds 1.5 ml; most hyaluronic acid syringes hold 1 ml. At AED 3,000 a syringe, Radiesse costs AED 2,000 per ml, inside the roughly AED 1,200 to 2,800 that branded hyaluronic acid filler costs per 1 ml syringe in Dubai. Bills climb because structural areas take several syringes, not because the product is unusually expensive.
The syringe counts below come from the FDA studies, Merz's UAE leaflet and one Dubai clinic's published treatment plan; the totals multiply them by the common AED 2,500 to 3,600 band.
| Area | Typical syringes (1.5 ml) | Based on | Typical total |
|---|---|---|---|
| Small area, such as the folds | 1 | A Dubai clinic's published treatment plan | AED 2,500 to 3,600 |
| Cheekbones | 1 to 2 | Cheek treatments typically use 2 to 3 ml in total | AED 2,500 to 7,200 |
| Full jawline | 2 to 3 | FDA jawline study: median 1.8 ml per side at the first session | AED 5,000 to 10,800 |
| Both hands | 2 to 4 | Merz UAE leaflet: at most 2 syringes per hand per session | AED 5,000 to 14,400 |
| Neck or décolletage, diluted | 1 per session, 2 or 3 sessions | FDA décolletage trial and expert consensus | AED 2,500 to 3,600 per session |
| Full face | 3 to 4 | The same clinic's published treatment plan | AED 7,500 to 14,400 |
Merz recommends no more than 10 ml of Radiesse a year, fewer than seven syringes, a useful ceiling if a plan starts to grow. Confirm the syringe size, because a quote "per syringe" means little without it, and treat very cheap offers with extra suspicion: whatever goes in, no enzyme can take it out. Our guide to dermal filler prices in Dubai explains how to compare quotes fairly.
Radiesse for the hands: cost and recovery
A Radiesse hand treatment typically uses two to four syringes, AED 5,000 to 14,400 at the prices most Dubai clinics publish, and brings more downtime than the face. The FDA approved it for the backs of the hands in June 2015, and the hands are an indication in Merz's UAE leaflet. It restores padding that thins with age, although very severe fat loss, with markedly visible veins and tendons, has not been studied. The leaflet's hand data are worth reading first:
- Temporary difficulty using the hands was reported by 48% of study patients, and by 68% of those with darker skin (Fitzpatrick types IV to VI).
- Lumps or bumps were reported by 12% and can last up to a year.
- Swelling can be significant, so rings come off before treatment and stay off until it settles.
- No more than 3 ml, two syringes, per hand in one session; larger volumes have not been studied.
Book it before a stretch of lighter days, not the week you need your hands for work, training or an event.
How long Radiesse lasts
Radiesse usually lasts about 12 to 18 months, the range Merz gives on its Middle East product page; its US materials put the upper end at up to two years. The FDA data fit: in the jawline study, 67.3% of patients who had responded at 12 weeks still showed the improvement at 48 weeks, and in the décolletage study the responder rate stayed above 60% at 60 weeks.
Your own result depends on age, metabolism and how much the area moves. For diluted treatments, expert consensus suggests a maintenance session within 12 to 18 months. Merz also states that it is not known whether Radiesse is safe or effective beyond three years in the face or one year in the hands.
Radiesse vs Sculptra vs hyaluronic acid filler
Radiesse sits between the other two: like hyaluronic acid it lifts on the day, like Sculptra it builds collagen over the following months, and unlike hyaluronic acid it cannot be dissolved.
| Radiesse (CaHA) | Sculptra (PLLA) | Hyaluronic acid filler | |
|---|---|---|---|
| How it works | Gel lifts on the day; microspheres then stimulate collagen | Stimulates collagen; adds little on the day | Gel adds volume directly and holds water |
| When you see it | Immediately, then builds over weeks | Gradually, over a course of about three sessions | Immediately |
| How long it lasts | About 12 to 18 months | Up to about two years | Several months to about two years, by product and area |
| Reversible? | No reversal agent | No | Yes, with hyaluronidase |
| Typical uses | Cheekbones, jawline, folds, hands; diluted for neck and décolletage | Gradual, all-over volume loss and skin quality | Lips, under-eyes, nose, cheeks, jawline, fine lines |
| Dubai price (2026) | AED 1,499 to 4,500 per 1.5 ml syringe | About AED 1,800 to 3,800 per vial | About AED 1,200 to 2,800 per 1 ml syringe |
Radiesse vs Sculptra. Choose by timing and the kind of change you want. Radiesse gives definition you can see as you leave the clinic, which suits a jawline or cheekbone that needs an edge. Sculptra, a poly-L-lactic acid product, builds a softer, all-over result across a course of treatments, which suits a face that has thinned generally. Neither can be reversed, and our Sculptra guide covers its course, timing and risks.
Radiesse vs hyaluronic acid filler. Hyaluronic acid is the safer default for soft or mobile areas, for a first filler, or for anyone who wants the option to reverse. Radiesse earns its place for firm structure over bone and a result that tends to outlast the softer hyaluronic acid gels. If you are unsure how a change will look on your face, trying it first with hyaluronic acid is the lower-risk way to find out.
Hyperdilute Radiesse: skin quality, not volume
Hyperdilute Radiesse is the same product mixed with saline or lidocaine so it spreads thinly under the skin, trading almost all of the immediate volume for collagen stimulation over a wider area. A 2019 expert consensus defines it as a 1.5 ml syringe plus at least 1.5 ml of diluent and suggests these starting points:
- Face: diluted 1:1, usually one syringe per session.
- Neck: 1:2 to 1:4 depending on skin thickness, usually one syringe per session.
- Décolletage: 1:2 to 1:4, half to one syringe per session.
- Upper arms: 1:2 to 1:4, half to one syringe per arm per session.
Two caveats. Merz funded that consensus. And only one diluted use has had a full regulatory review: in March 2026 the FDA approved Radiesse diluted 1:2 with saline for wrinkles on the décolletage. The trial enrolled 152 women aged 30 to 65; the treatment group had three sessions, at the start, week 6 and week 12, and at week 24, 71.2% had improved by at least one grade, against 6.3% of an untreated control group. Injections stay off the breast tissue itself. Neck, arm and body use remains outside the approved uses.
Diluted Radiesse will not lift heavy sagging; it improves crepey texture and firmness modestly over a few months. If laxity is your main concern, our guide on how to tighten loose skin in Dubai compares the options that address it more directly.
The safety fact that matters most: Radiesse cannot be dissolved
Radiesse cannot be dissolved. Hyaluronidase, the enzyme that breaks down hyaluronic acid filler, does not dissolve calcium hydroxylapatite, and a 2024 review in the Aesthetic Surgery Journal states that there is no reversal agent for it. Merz's UAE leaflet puts it another way: more product can easily be added later, but it cannot easily be removed.
The most typical complication is a nodule, a small firm lump of product. The review sets out a stepped approach: leave lumps that cannot be seen, since they tend to fade as the material breaks down; disperse visible ones with massage and injections of saline, sterile water or lidocaine; then try steroid or 5-fluorouracil injections or laser; and keep surgical removal as a last resort. Sodium thiosulfate, sometimes described online as a Radiesse dissolver, did not break down the microspheres in a controlled animal study, and the authors do not recommend it. Visible lumps are easier to treat early, before much new collagen forms around them.
The rarer, more serious risk, shared with every filler, is product entering or pressing on a blood vessel; the labelling lists vision impairment, blindness, stroke and skin necrosis among the rare outcomes. With hyaluronic acid filler a clinic can inject hyaluronidase to break the gel down, as our guide to filler dissolving in Dubai explains. With Radiesse there is no antidote, so prevention carries the weight: an injector who knows the anatomy, injects slowly with low pressure, and avoids the nose and the area between the brows.
Contact the clinic immediately, or go to an emergency department, if you notice pale, blotchy or dusky skin near the injection site, pain that is getting worse rather than better, any change in your vision, or signs of a stroke such as sudden weakness or difficulty speaking. See the clinic within days for a lump that is growing, or for redness, warmth or fever, which can signal infection.
Also from the labelling: Radiesse shows up on X-rays and CT scans, so tell your doctor and any radiologist that you have had it. A tendency to keloids or thickened scars, active infection or inflammation in the area, and bleeding disorders are reasons not to treat, and safety has not been established in pregnancy or breastfeeding.
Recovery, and choosing an injector in Dubai
Recovery from facial Radiesse is usually quick, but choosing the injector is the decision that matters most, because the result cannot be reversed. Merz puts a typical Radiesse injection appointment, consultation included, at about 30 minutes. Redness and bruising usually settle in a day or two, though the UAE leaflet warns that swelling can take 7 to 10 days, occasionally several weeks. It advises ice for about 24 hours, keeping the face fairly still for a week, and avoiding sun, tanning lamps, saunas and intensive facial treatments; in a Dubai summer, skip the beach and outdoor sport until the swelling has settled.
Before you book, check these five things:
- A licensed doctor in a licensed clinic. That means a DHA licence in Dubai, DOH in Abu Dhabi or MOHAP in the northern emirates. Check both the clinic and the injector on the registry before you pay a deposit.
- Specific Radiesse experience. Ask how often they inject it, in which areas, and how they would manage a nodule or a blocked vessel without an enzyme to fall back on.
- The sealed product. Genuine Radiesse comes in a sealed foil pouch with a batch number and a use-by date. It needs no fridge, but Merz's UAE leaflet specifies storage at 15 to 25 °C.
- A written plan. The syringe size, the number of syringes, the total price, and whether a review appointment is included.
- The right answer on lips and under-eyes. A clinic that offers Radiesse for either is telling you something about its judgement.
If you would rather not work all this out alone, tell us what you want to treat and where you are in the UAE, and we will match you with licensed clinics and ask for an itemised quote per syringe.
Sculptra in Dubai
How poly-L-lactic acid rebuilds collagen over a course of sessions.
SafetyFiller dissolving in Dubai
How hyaluronidase reverses hyaluronic acid filler, and when it is needed.
BrandsJuvederm vs Restylane
The two big hyaluronic acid ranges compared, area by area.
Skin qualitySkin boosters in Dubai
Profhilo and other boosters for hydration rather than volume.